According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. The top benefits of nattokinase include the following: Regulate blood pressure. This condition is due to the pooling of blood in the veins of the lower legs. Berberine is a compound extracted from several plants. 4. The most effective blood sugar-lowering dose was 200 mg/day higher doses had no further benefit [33]. The extract has been widely studied for the past 40 . Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. Prunes and prune juice have many health benefits. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. Pycnogenol-treated patients had significant improvement in symptoms as well as a reduction in leg swelling as compared to those not receiving treatment. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. 3. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. Grapes: Health Benefits, Nutrition, Recipes and Risks - Dr. Axe Natural Factors Pycnogenol 100mg 30 Veggie Caps. However, research on these two groups is limited [71, 15]. Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. The usual recommended duration of treatment for topical application is 7 days for Pycnogenol cream and 6 weeks for Pycnogenol powder. The results of a 2013 animal study suggest that pine bark extract may help to reduce damage to nerve cells following a traumatic brain injury. Vertigo. A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. (2004). Required fields are marked *. The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. Studies have been conducted to review the effects of pine bark extract on pseudomonas infectious wounds. That said, there are some instances where this extract may possibly be effective. (2017). Lets begin with asthma. She loves communicating science and empowering people to achieve their optimal health. Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. Read More: Health Benefits of Peanut Butter. All rights reserved. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. (2012). 6 Vinpocetine Benefits + How It Works & Side Effects A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. Pycnogenol Benefits, Dosage & Side Effects - Ayur Times Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Eye health. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. It can also stabilize mast cells, which release histamine and trigger allergic reactions. Improve cardiovascular health. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. 8 Proven Benefits of L-arginine - Nutrition and Fitness Central 12 Benefits of Pycnogenol (Pine Bark Extract) According to Studies But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? Protection from inflammation, immunosuppression and carcinogenesis It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. While much of this is positive, it will be a while before doctors routinely recommend this dietary supplement for these conditions. There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. The first studied group included 66 healthy subjects in whom the number of muscle cramps was recorded two weeks before entering the study and during the fourth and fifth week. There were 88 in the control group and 81 in the Pycnogenol group. Neuroprotective effect of Pycnogenol® following traumatic brain injury. which enables users to obtain detailed information and reports based on their genome. It has many health benefits, and may help protect against several chronic conditions. , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. Typical doses range from 50 milligrams to 450 milligrams per day. Pine bark extract may be the perfect treatment since its an antioxidant dynamo. There is currently insufficient evidence to determine what a safe and effective dose of lysine is for specific conditions. from the bark of the French maritime pine tree. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). Thirty patients with diabetic ulcers were treated with 150 mg Pycnogenol daily for four weeks and another group of 30 comparable patients received no treatment. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Most anal fissures heal with home treatment after a few days or weeks. But what are its health benefits? In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. A Pycnogenol combination product (with l-arginine, alpha lipoic acid, B vitamins, and vitamin K2) may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [39]. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. Dr. Drew explains the benefits of probiotics for the gut microbiome and talks about the rise of leaky gut, and Dr. Steve shares how emotional stress can have real physical effects on the heart. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. In a good-quality study, 77 patients with osteoarthritis were treated with 100 mg of Pycnogenol daily and 79 patients were treated with placebo for three months. Disease of the retina in the eye. A sitz bath, which involves sitting in warm water for 10 minutes, twice daily, is helpful to patients with anal itching, aching or burning and is known as one of the best ways to get rid of hemorrhoids fast. When pycnogenol cream was added to oral supplements in a small study of 18 people with vein ulcers, it helped ulcers heal more quickly [26]. Staves Off Infections. Prenatal nutrition can be confusing. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. According to a meta-analysis of 9 trials including 549 people, 150-200 mg/day for at least 12 weeks may reduce both diastolic and systolic blood pressure [36]. Treatment of ADHD with French maritime pine bark extract, Pycnogenol [Abstract]. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. . Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. In a study of 20 postmenopausal women, 12 weeks of pycnogenol supplementation improved hydration and elasticity of the skin. In oneparticular study published in Research in Pharmaceutical Sciences, researchers investigated the antibacterial activity of pine bark extract essential oil on staph infections, E. coli and pseudomonas infections. Sort By. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. Potential for allergy when taken orally or used on the skin. PQQ Supplements: Overview, Benefits, and Side Effects - Healthline Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Healthline Media does not provide medical advice, diagnosis, or treatment. For that reason, you should be careful taking pine bark if you have hypertension or diabetes. Pycnogenol significantly improved the heavy feeling as well as the swelling. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. It is chronic venous insufficiency, a common disease among people who are obese or elderly and those who lead a sedentary lifestyle. Forty-seven Japanese men with mild erectile dysfunction were given supplementation L-arginine and French maritime pine bark extract over a period of time. Can you get pycnogenol naturally from foods? Pycnogenol seems well-tolerated for use in adults for up to 6 months. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . A clinical trial of 57 ADHD children found that daily Pycnogenol (1 mg/kg) for one month may reduce hyperactivity symptoms. The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD) [Abstract]. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. You can learn more about how we ensure our content is accurate and current by reading our. According to the lab results of 10 volunteers, a higher Pycnogenol dose (300 mg) may impact these enzymes after just 30 minutes [52]. The goal of this study was to evaluate if Pycnogenol could prevent deep venous thrombosis (DVT) and superficial vein thrombosis (SVT) in eight-hour flights in 196 subjects at risk of these conditions. A trial of 86 people with eye damage from diabetes found that antioxidant therapy (including pycnogenol, vitamin E, and Coenzyme Q10) may improve eye health and reduce reactive oxygen species levels [35]. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Video: Why You Need Zinc and Where to Find It. ", Panminerva Medica: "Supplementation with Pycnogenol improves signs and symptoms of menopausal transition.". Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. Pycnogenol French maritime pine bark extract's 4 basic properties. Some health benefits of Pycnogenol include:. But the actual bioavailability of this complex mixture is still unknown. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. There's good evidence that pycnogenol helps with eye damage caused by diabetes. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. Why Pycnogenol May Be the Only Supplement You'll Ever Need The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . There havent been enough studies yet to change practice protocols for treating children. Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. According to a study of 170 women, low-dose pycnogenol (60 mg/day) may improve menopausal symptoms over 3 months, including night sweats, hot flashes, insomnia and sleep problems [69]. A randomized placebo-controlled trial of 60 children with mild-to-moderate asthma found that those who took Pycnogenol may be able to reduce or discontinue their use of rescue inhalers more often than the placebo group [15]. Researchers suggest that it may have stronger benefits than elastic compression stockings. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. Another one of its exemplary effects is helping manage blood pressure levels. Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. blood in the urine. Next, the doctors discuss the link between salt and hypertension, and Dr. Steve gives his insight on drinking red wine for a healthy heart. What are the Benefits of Taking Beta 1 3D Glucan? - betterwayhealth Pycnogenol is the registered trademark name for a French formula. Although the preliminary studies show many health benefits with the use of Pycnogenol, future larger and better studies are needed. One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [17]. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. Pycnogenol helps erectile dysfunction and diabetes through circulatory link In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. Pycnogenol French maritime pine bark extract acts as a potent blend of antioxidants, it is a natural anti-inflammatory, stimulates generation of collagen and hyaluronic acid and help with natural dilation of blood vessels by supporting production of nitric oxide. Fundukian, L.J. In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. Researchers suggest this effect may be due to reduced dopamine and adrenaline levels and increased glutathione levels. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. The Benefits of DIM - Fort Wayne Physical Medicine Rakel, D. Integrative Medicine, 3rd edition, Saunders, 2012. ", Natural Medicines Comprehensive Database web site: "Pycnogenol.". A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. Pycnogenol in metabolic syndrome and related disorders [Abstract]. For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78]. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. Chanca Piedra: Benefits, Dosage, Side Effects, and More - Healthline Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. Diabetic retinopathy is a type of eye injury caused by complications from diabetes. Consequently, blood pressure is lowered. The results showed that the combination of local and systemic applications of Pycnogenol were the best in terms of ulcer healing even though local application of Pycnogenol also speeded up ulcer healing. Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. Pycnogenol can help control blood pressure, which helps improve overall heart health. Animal studies have found that gotu kola makes it harder . Joe Cohen flipped the script on conventional and alternative medicine and it worked. However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. Pycnogenol Why Should Men Like You Care? - ManTripping A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. . Pycnogenol can help control blood pressure, which helps improve overall heart health. The combination of Panax ginseng and vitamin E also appears to have an effect. The dosage in most clinical studies varied between 50-360 mg/day. Infants and children may not be able to synthesize enough of it, but it is present in many protein-rich . In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. whole-body health. New research shows . Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. Eliminate blood clots. Pycnogenol has four main components that contribute to its benefits for men's health. Some small studies suggest it may also protect against coronary artery disease and blood clots. In a small/preliminary study of kids with asthma, pycnogenol helped improve symptoms. If you choose to use Pycnogenol, follow the dosage instructions on the label. Used early on, it may prevent eye damage and blindness from diabetes [34]. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. $47.99. Pycnogenol is a compound of natural chemicals. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. All rights reserved. He later extracted proanthocyanidins from the European coastal pine tree, which he named Pycnogenol.. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. Its likely that muscle recovery time improved as well due to the high antioxidants pine bark extract contains. Pycnogenol is the US trademarked name for an antioxidant made from Mediterranean tree bark. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Side Effects of Pycnogenol. Studies have shown that the tree bark can help decrease common symptoms including hot flashes, mood swings, irregular periods, and others. Pycnogenol is a standardized supplement formula guaranteed to contain at least 65-75% proanthocyanidins, the active . In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. After stopping Pycnogenol for one month, symptoms Gotu Kola: Health Benefits, Side Effects, Uses, and More - WebMD Boost gastrointestinal health. Pycnogenol may help with other conditions as well. Pycnogenol seems to help with asthma and allergies. Seems like it must be pretty amazing, but lets look closer. Early research shows that taking it at least 5 weeks before the start of allergy season seems to lessen symptoms. Here are the many health benefits believed to be possible with Pycnogenol: Now lets dive into the first condition it could help treat. A 2006 study found that children who took a daily pine bark extract supplement for four weeks had significantly lower levels of hyperactivity. $109.99. Diarrhea. 4 Items . Last medically reviewed on January 24, 2018. Tell your doctor about any supplements you're taking, even if they're natural. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. It also reduced the size of scars. (14, 15). Pycnogenol may stimulate the immune system. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. (2017). Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . are clickable links to medically peer-reviewed studies. We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. Based on another study of 6 trained and 7 untrained people, an antioxidant combination product containing Pycnogenol (Lactaway) may increase endurance. Considering that about 1 of 3 adults in the U . The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people.